Posology : מינונים

4.2 Posology and method of administration

The duration of treatment varies according to the indication and the severity of the infection.

Adults
250mg once daily.

Skin infections
Recommended duration of treatment:
• Tinea pedis (interdigital, plantar/moccasin type): 2 to 6 weeks.
• Tinea corporis, cruris: 2 to 4 weeks.
• Cutaneous candidiasis: 2 to 4 weeks.
Complete resolution of the signs and symptoms of infection may not occur until several weeks after mycological cure.
Hair and scalp infections
Recommended duration of treatment:
• Tinea capitis: 4 weeks.
Tinea capitis occurs primarily in children

Onychomycosis
For most patients the duration of successful treatment is 6 to 12 weeks.
Fingernail onychomycosis: Six weeks of therapy is sufficient for fingernail infections in most cases.
Toenail onychomycosis: Twelve weeks of therapy is sufficient for toenail infections in most cases.
Some patients with poor nail outgrowth may require longer treatment. The optimal clinical effect is seen some months after mycological cure and cessation of treatment.
This is related to the period required for outgrowth of healthy nail.

Special population

Hepatic impairment
Terbinafine Teva 250 mg are not recommended for patients with chronic or active hepatic disease (see sections 4.3 Contraindications and 4.4 Special warnings and precautions for use).

Renal impairment
The use of oral terbinafine has not been adequately studied in patients with renal impairment and is therefore not recommended in this population (see section 4.4 Special warnings and precautions for use and section 5.2 Pharmacokinetic properties).
Children
A review of safety experience with oral terbinafine in children, which includes 314 patients involved in the UK terbinafine Post Marketing Surveillance study, has shown that the adverse event profile in children is similar to that seen in adults. No evidence of any new, unusual or more severe reactions to those seen in the adult population have been noted. However, as data is still limited its use is not recommended.Geriatric patients
There is no evidence to suggest that elderly patients (aged 65 years or above) require different dosages or experience side effects different to those of younger patients. When prescribing Lamisil tablets for patients in this age group,the possibility of pre-existing impairment of liver or kidney function should be considered (see Precautions).
Method of administration
The scored caplets are taken orally with water. They should preferably be taken at the same time each day and can be taken on an empty stomach or after a meal.
Terbinafine Teva 250mg scored tablets are divisible and can be divided into two equal parts (i.e., 125 mg strength).The caplets cannot be crushed due to a bitter taste.