Posology : מינונים

4.2 Posology and method of administration

Adults and elderly patients
The painful area should be covered with the plaster once daily for up to 12 hours within a 24 hours period.
Only the number of plasters that are needed for an effective treatment should be used. When needed, the plasters may be cut into smaller sizes with scissors prior to removal of the release liner. In total, not more than three plasters should be used at the same time.
The plaster must be applied to intact, dry, non-irritated skin (after healing of the shingles).
Each plaster must be worn no longer than 12 hours. The subsequent plaster-free interval must be at least 12 hours.
The plaster can be applied during the day or during the night.
The plaster must be applied to the skin immediately after removal from the sachet and following removal of the release liner from the gel surface. Hairs in the affected area must be cut off with a pair of scissors (not shaved).

Treatment outcome should be re-evaluated after 2-4 weeks. If there has been no response to Versatis® 700 mg after this period (during the wearing time and/or during the plaster-free interval), treatment must be discontinued as potential risks may outweigh benefits in this context (see sections 4.4 and 5.1). Long-term use of Versatis® 700 mg in clinical studies showed that the number of plasters used decreased over time. Therefore treatment should be reassessed at regular intervals to decide whether the amount of plasters needed to cover the painful area can be reduced, or if the plaster-free period can be extended.
Renal impairment
In patients with mild or moderate renal impairment a dosage adjustment is not required.
Versatis® 700 mg should be used with caution in patients with severe renal impairment (see section 4.4).

Hepatic impairment
In patients with mild or moderate hepatic impairment a dosage adjustment is not required.
Versatis® 700 mg should be used with caution in patients with severe hepatic impairment (see section 4.4).

Paediatric population
Versatis® 700 mg is not indicated in children below 18 years. No data are available.