Adverse reactions : תופעות לוואי

4.8   Undesirable effects

During clinical studies, the most commonly reported adverse events after the first dose were reactions at the injection site, including soreness, redness and swelling.
Frequencies are reported as:
Common:        (≥ 1/100 to < 1/10)
Very rare:     (< 1/10,000)

Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness.

General reactions that may occur in temporal association with Typherix vaccination include: 
Clinical studies

Nervous system disorders:
Common: headache
Gastrointestinal disorders:
Common: nausea

Skin and subcutaneous tissue disorders:
Common: itching

General disorders and administration site conditions:
Common: fever, general aches, malaise
Following a second dose, there was an increased incidence of redness and soreness (>10%).

Local reactions were usually reported during the first 48 hours and systemic reactions were also transient.

Post-marketing

The following reactions have been reported in post-marketing experience: 
Skin and subcutaneous tissue disorders:
Very rare: urticaria

Immune system disorders:
Very rare: anaphylaxis, allergic reactions, including anaphylactoid reactions