Contraindications : התוויות נגד

4.3 Contraindications
All forms of hyperkalaemia as may occur in marked renal failure (even when not yet associated with manifest hyperkalaemia), untreated Addison's disease, hyporeninaemic hypoaldosteronism, acute dehydration and conditions involving extensive cell destruction (e.g. severe burns).
Hypersensitivity to potassium administration e.g. hyperkalaemic periodic paralysis and congenital paramyotonia, or hypersensitivity to any of the excipients.
Hyperkalemic periodic paralysis: It is an inherited autosomal dominant disorder which affects sodium channels in muscle cells and the ability to regulate potassium levels in the blood. The term hyperkalemic is misleading since patients are often normokalemic during attacks. The fact that attacks are precipitated by potassium administration best defines the disease.
All solid forms of potassium medication are contraindicated in the presence of obstructions in the digestive tract (e.g. resulting from compression of the oesophagus due to dilation of the left atrium or from stenosis of the gut).
In cases of metabolic acidosis, the hypokalaemia should be treated not with potassium chloride but with an alkaline potassium salt (e.g. potassium bicarbonate).
Concomitant treatment with potassium sparing diuretics (e.g. spironolactone, triamterene, amiloride) (See also section 4.5 Interaction with other medicinal products and other forms of interaction).


SLO API JUN16 CL V3                               REF Ireland_PI_effective_Feb-2016 Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.