Posology : מינונים

4.2 Posology and method of administration
It is important that the tablets should be swallowed whole, with fluid during meals, whilst the patient is sitting upright.
General Populations:
The dosage of Slow-K should be adjusted to the individual needs of each patient. 2-3 tablets daily are usually an adequate supplement to prevent hypokalaemia. In states of potassium deficiency doses of 5 to 6 tablets daily may be needed increasing up to 12 tablets daily in severe deficiency. If the dosage exceeds 16mmol K+ (2 tablets) it should be taken in divided doses. Where intermittent diuretic therapy is being used, it is advisable to give Slow K on intervening days between administration of the diuretic. The response to treatment should preferably be monitored by repeat determination of plasma potassium and Slow K continued until the hypokalaemia has been corrected.


SLO API JUN16 CL V3                                   REF Ireland_PI_effective_Feb-2016 Special populations
Renal impairment
In patients with mild to moderate renal impairment, Slow K should be given with extreme caution with frequent serum potassium monitoring due to increased risk of hyperkalemia. Slow-K is contraindicated in patients with severe renal impairment (see also section 4.3 Contraindications).
Hepatic impairment
No studies have been performed in hepatically impaired patients. However, Slow-K should be given with caution due to increased likelihood of electrolyte disturbances in patients with hepatic impairment (see also section 4.3 Contraindications).
Paediatrics
Safety and effectiveness in children have not been established, Slow-K is therefore not recommended for paediatric use.
Geriatrics (older than 65 years)
Slow-K should be given with caution and with frequent serum potassium monitoring due to increased risk of hyperkalemia.
Method of administration
Slow-K is advised to be given with or after food to minimize gastric irritation. The sugar-coated tablets must not be crushed, chewed, or sucked, but should be swallowed whole with an adequate amount of fluid while the patient is sitting upright.