Contraindications : התוויות נגד

4.3. Contraindications
Patients with known hypersensitivity to ibuprofen or any other constituent of the medicinal product.

NUROFEN® LIQUID CAPSULES 200mg                                                      April 2015 Patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis, angioedema, or urticaria) in response to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs).

Active or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).

Patients with a history of, or existing peptic ulceration gastrointestinal ulceration/perforation or bleeding, including that associated with NSAIDs (see section "special warnings and precautions for use").

Patients with severe hepatic failure, severe renal failure or severe heart failure (see also section "special warnings and precautions for use").

During the last trimester of pregnancy as there is a risk of premature closure of the fetal ductus arteriosus with possible persistent pulmonary hypertension. The onset of labor may be delayed and the duration increased with an increased bleeding tendency in both mother and child (see section "pregnancy and lactation").