Pregnancy & Lactation : הריון/הנקה

    4.6 Fertility, pregnancy and lactation
Pregnancy
There are no controlled studies on the administration of betamethasone during pregnancy and lactation available.
In animal studies the use of glucocorticoids led to foetal malformations (see section 5.3). An increased risk of cleft palate in human foetus by the administration of glucocorticoids during the first trimester is under discussion. If glucocorticoids are administered at the end of pregnancy, there is a risk for the foetus of atrophy of the adrenal cortex, and substitution treatment of the new-born may be required. Furthermore, they will also need to be tested for the rare occurrence of congenital cataracts.
For this reason, Betnesol should only be administered during pregnancy if the expected benefit outweighs the potential risk for the foetus.
Generally speaking, no cortisone-containing medicinal products should be administered in the first 3 months of pregnancy.
Breastfeeding
Since glucocorticoids penetrate breast milk in small quantities, breastfeeding should be stopped during glucocorticoid treatment.

Fertility
No data are available on effects on fertility