Posology : מינונים

4.2    Posology and method of administration
Posology

Intravenous bolus injection:
Normal dose is 50 to 100 micrograms, which can be repeated until the desired effect is attained. The doses may be increased in the case of severe hypotension, but must not exceed a bolus of 100 micrograms.

Continuous infusion:
Initial dose is 25 to 50 micrograms/min. Doses can be increased up to 100 micrograms/min or reduced in order to maintain systolic blood pressure close to its reference value.

Doses between 25 and 100 micrograms/min have been considered effective in maintaining maternal blood pressure.
Renal impairment
Lower doses of phenylephrine may be needed in patients with impaired renal function.

Hepatic Impairment
Higher doses of phenylephrine may be needed in patients with cirrhosis of the liver.

Older people:
Treatment of the elderly should be carried out with care.
Paediatric population
The safety and efficacy of phenylephrine in children have not been established. No data are available.

Method of administration:
Parenteral administration. Intravenous bolus injection or intravenous infusion.
The pre-filled syringe is not suitable for use with a syringe pump.
Phenylephrine Aguettant 50 mcg/ml should only be administered by healthcare professionals with appropriate training and relevant experience.