Posology : מינונים

4.2 Posology and method of administration

Posology
Adults and adolescents
Ephedrine must be administered at the lowest effective dose over the shortest possible period of time.
Adjust the dosage of Ephedrin Sintetica on case-by-case basis depending on the cardiovascular and hemodynamic parameters. The following dosage is provided for guidance purposes only.

Adults:
5-25 mg i.v., administered slowly.
It is recommended that Ephedrin Sintetica be administered in divided doses of 5-10 mg until the blood pressure normalizes.

Maximum daily dose (150 mg/24h).
Ephedrin Sintetica can also be administered s.c or i.m. The dose is 25-50 mg (range 10- 50 mg). If necessary, a second of 50 mg dose may be administered i.m, or 10-25 mg administered i.v.

Children:
The recommended pediatric dose is 3 mg/kg per day (750 micrograms/kg per dose) or 100 mg/m² per day (25 mg/m2 per dose) in 4-6 doses per day, administered s.c. or i.v.
The bolus i.v. dose for hypotension is 0.1-0.3 mg/kg.

When administered intravenously, the injection should be given slowly.

Elderly patients
As for adults, starting from 5 mg boluses.
Method of administration
Ephedrine must be used solely by or under the supervision of the anaesthetist.