Posology : מינונים

4.2   Posology and method of administration

Adults: The usual recommended dosage of Klacid SR Tablets in adults is one 500mg modified-release tablet daily to be taken with food . In more severe infections, the dosage can be increased to two 500mg modified-release tablets daily. The usual duration of treatment is 6 to 14 days.

Children older than 12 years: As for adults.

Children younger than 12 years: Use of Klacid SR are not recommended for children younger than 12 years. Clinical trials have been conducted using clarithromycin peadiatric suspension in children 6 months to 12 years of age.
Therefore, children under 12 years of age should use clarithromycin peadiatric suspension (granules for oral suspension).

In patients with renal impairment with creatinine clearance less than 30 mL/min, the dosage of clarithromycin should be reduced by one-half, i.e.
250 mg once daily, or 250 mg twice daily in more severe infections. Treatment should not be continued beyond 14 days in these patients. Because the tablet cannot be split, the dose cannot be reduced from 500 mg daily, Klacid SR Tablets should not be used in this patient population (see section 4.3).