Posology : מינונים

4.2       Posology and method of administration
Dosage
•    For routine boosters, a single dose of 0.5 ml should be givenevery 10 years.
•    For primary vaccination, 3 successive doses of 0.5 ml should be administered 1 month apart..
•    For prophylaxis in people exposed to a risk of tetanus, the following recommended schedule should be followed:

PATIENT NOT IMMUNISED                                      PATIENT FULLY IMMUNISED TYPE                            OR                                                   Time since last booster OF INJURY                         VACCINATION                                 5 to 10 years               >10 years INCOMPLETE
Start or complete                            No injection                           Tetanus toxoid: 1 dose Minor – clean                vaccination:                                                                        of 0.5 ml Tetanus toxoid 1 dose of
0.5 ml
Major - clean or             In one arm:                                                                         In one arm: tetanus-prone                Human tetanus                                                                       Human tetanus immunoglobulin, 250 IU*                                                             immunoglobulin, 250 IU* In the other arm:                                                                   In the other arm: Tetanus toxoid**: 1 dose of                  Tetanus toxoid: 1 dose                 Tetanus toxoid: 1 dose of 0.5 ml                                       of 0.5 ml                              0.5 ml* In one arm:                                                  In one arm: Human tetanus                                                Human tetanus Tetanus-prone         immunoglobulin, 500 IU*                                      immunoglobulin, 500 IU* Delayed or            In the other arm:                                            In the other arm: incomplete            Tetanus toxoid**: 1 dose of      Tetanus toxoid: 1 dose      Tetanus toxoid: 1 dose of debridement           0.5 ml                           of 0.5 ml                   0.5 ml* Antibiotic therapy               Antibiotic therapy          Antibiotic therapy *Use different syringes, needles and injection sites.
**Update the vaccination status according to the vaccination schedule.
Paediatric population
Not applicable.
Method of administration
Precautions to be taken before handling or administering the medicinal product Given the adsorbed nature of the vaccine, it is preferable to administer it intramuscularly (IM) in order to minimise local reactions. The recommended sites are: the anterolateral aspect of the thigh or arm.
Deep subcutaneous (SC) injection may also be used.
However, intradermal injection should not be used.
See "Special precautions for disposal and other handling", [section] 6.6.