Indications : התוויות

4.1      Therapeutic indications

-   For the treatment of duodenal and gastric ulcer.
-   Treatment and prevention of NSAID induced ulcers lesions, erosions, while NSAID therapy continues.
-   Use in conjunction with Mifepristone subject to the approval of a committee for the termination of pregnancy according to the Israeli penal law 1977.
Failure of pregnancy in the first trimester
The usage is intended for emptying the uterus in a states of first trimester pregnancy failure, including: presentation of a pregnancy sac in the uterus with no fetal echo, missed abortion (until week 11+6 and a fetus length of 40 mm) or incomplete abortion. The preparation is to be used after location of the sac in the uterus has been proved and the diagnosis of pregnancy failure is certain.The preparation can be used for this purpose in an ambulatory setting. The dosage and route of administration will be similar to the use of Cytotec® in pregnancy termination after using Mifegyne. Informed consent and medical surveillance are required .

-   Softening and dilation of the cervix for performing intra-uterine procedures such as: curetage, hysteroscopy, IUD insertion and others, according to clinical judgment.
The preparation can be used for this purpose in an ambulatory setting The route of administration (vaginal,sublingual, buccal, oral or rectal) and the dosage are according to the decision of the attending doctor.