Pharmaceutical particulars : מידע רוקחי

6.    PHARMACEUTICAL PARTICULARS
6.1   List of excipients

Nirmatrelvir film-coated tablets

Tablet core:

Microcrystalline cellulose
Lactose monohydrate
Croscarmellose sodium
Colloidal silicon dioxide
Sodium stearyl fumarate

Film coat (Opadry Pink):
HPMC 2910/Hypermellose
Titanium dioxide
Macrogol/PEG
Iron oxide red
Ritonavir film-coated tablets

Tablet core:
Copovidone
Calcium hydrogen phosphate
Sorbitan laurate
Sodium stearyl fumarate
Silica, colloidal anhydrous
Ethanol (It will not appear in the final product except in trace)

Film coat ( Opadry White):
HPMC 2910/Hypromellose 6cp (E464)
Titanium dioxide (E171)
Macrogol /PEG ,MW 400(E1521)
Hydroxypropyl cellulose (E463)
Talc (E553b)
Macrogol/PEG, MW 3350,
MACROGOL 4000 (E1521)
Silica, colloidal anhydrous (E551)
Polysorbate 80 (E433)
6.2   Incompatibilities

Not applicable.

6.3   Shelf life
The expiry date of the product is indicated on the packaging materials 
6.4   Special precautions for storage

This medicine does not require any special storage conditions. It is recommended to keep at room temperature

6.5   Nature and contents of container

OPA/Al/PVC foil blister cards of 30 tablets.
Paxlovid is packaged in cartons containing 5 daily-dose blister cards of 30 tablets.

Each daily blister card contains 4 nirmatrelvir tablets and 2 ritonavir tablets for morning and evening dose.



6.6   Special precautions for disposal

No special requirements for disposal.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.