Quest for the right Drug
דפו-פרוברה 500 DEPO-PROVERA 500 (MEDROXYPROGESTERONE ACETATE)
צורת מתן:
תוך-שרירי : I.M
צורת מינון:
תרחיף להזרקה : SUSPENSION FOR INJECTION
עלון לרופא
מינוניםPosology התוויות
Indications תופעות לוואי
Adverse reactions התוויות נגד
Contraindications אינטראקציות
Interactions מינון יתר
Overdose הריון/הנקה
Pregnancy & Lactation אוכלוסיות מיוחדות
Special populations תכונות פרמקולוגיות
Pharmacological properties מידע רוקחי
Pharmaceutical particulars אזהרת שימוש
Special Warning עלון לרופא
Physicians Leaflet
Interactions : אינטראקציות
4.5 Interaction with other medicinal products and other forms of interaction
Aminoglutethimide, when administered concomitantly with high doses of Depo-Provera®, can 2. QUALITATIVE AND QUANTITATIVE COMPOSITION significantly reduce serum levels of medroxyprogesterone acetate. The possibility of reducing
Depot-medroxyprogesterone acetate injectable suspension is available as 500 mg/3.3 ml vial. the efficacy of high doses of Depo-Provera® should be taken into consideration when using Excipients with known effect: aminoglutethimide simultaneously.
Methyl paraben Medroxyprogesterone acetate (MPA) is metabolized in vitro primarily by hydroxylation via the Propyl paraben CYP3A4. Specific drug-drug interaction studies evaluating the clinical effects of CYP3A4 inducers Sodium chloride or inhibitors on MPA have not been conducted and therefore the clinical effects of CYP3A4 inducers For the full list of excipients, see section 6.1. or inhibitors are unknown.
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