Indications : התוויות

4.1 Therapeutic indications

Cefazolin - Fresenius is indicated in the treatment of the following serious infections due to susceptible organisms:

Respiratory Tract Infections: Due to S.Aureus (methicillin sensitive).

Species for which acquired resistance can be a problem: S. pneumoniae, H.influenzae, and group A beta-hemolytic streptococci.

Injectable benzathine penicillin is considered to be the drug of choice in treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever.

Data establishing the efficacy of Cefazolin - Fresenius in the subsequent prevention of rheumatic fever are not available at present.

Urinary Tract Infections: Due to E coli.

Skin and Skin Structure Infections: Due to S. Aureus (methicillin sensitive).
Species for which acquired resistance can be a problem: group A beta-hemolytic streptococci, and other strains of streptococci.

Biliary Tract Infections: Due to E coli, S. aureus. Species for which acquired resistance can be a problem: various strains of streptococci.

Bone and Joint Infections: Due to S. aureus.

Genital Infections: (i.e., prostatitis, epididymitis) due to E. Coli.
Septicemia: Due to, S. aureus (methicillin sensitive), E coli. Species for which acquired resistance can be a problem: S. pneumonia.

Endocarditis: Due to S. aureus (methicillin sensitive).
Species for which acquired resistance can be a problem: group A beta-hemolytic streptococci.

Perioperative Prophylaxis: The prophylactic administration of Cefazolin - Fresenius preoperatively, intraoperatively, and postoperatively may reduce the incidence of certain postoperative infections in patients undergoing surgical procedures which are classified as contaminated or potentially contaminated (e.g., vaginal hysterectomy, and cholecystectomy in high-risk patients such as those older than 70 years, with acute cholecystitis, obstructive jaundice, or common duct bile stones).

The perioperative use of Cefazolin - Fresenius may also be effective in surgical patients in whom infection at the operative site would present a serious risk (e.g., during open-heart surgery and prosthetic arthroplasty).