Posology : מינונים

4.2      Posology and method of administration a)       Dissolution and metaphylaxis of uric acid stones:
In general, take 4 measuring spoonfuls (= 10 g granules equivalent to 88 mmol alkali) daily divided into three doses, after meals.
Take 1 measuring spoonful every morning, 1 measuring spoonful at midday and 2 measuring spoonfuls every evening.
The pH of the fresh urine should be within the range of pH 6.2 – 6.8.
If the pH reading is below the recommended zone, the daily dose should be increased by half a measuring spoonful Uralyt-U (11 mmol alkali) in the evening. If the pH reading is above the recommended zone, the daily dose should be reduced by half a measuring spoonful (11 mmol alkali) in the evening.
The correct dose has been reached if the pH of the fresh urine, before taking the dose of Uralyt-U, is within the recommended range.
For metaphylaxis of uric acid stones, regular checks of the urine pH are advisable.
b)    Metaphylaxis of calcium-containing renal calculi:
The daily dose should be 2 - 3 measuring spoonfuls (= 5 - 7.5 g granules equivalent to 44 mmol - 66 mmol alkali) and should be taken in a single dose in the evening. If the pH reading is too low, 3 - 4.5 measuring spoonfuls (= 7.5 g - 11.25 g granules equivalent to 66 mmol - 99 mmol alkali) should be taken in 2-3 doses divided over the day, after meals.
A urine pH reading of 7.0 should be aimed at. The pH should not fall below pH 6.2 and should not rise above pH 7.4.
Citrate levels and/or urine pH readings should be regularly checked and the individual dose (see above) adjusted accordingly.


Method of administration:
The granules should be taken as a solution in a glass of water.

Measurement of urine pH:
Immediately before taking each dose, a test strip of the indicator paper enclosed in this pack should be wetted with fresh urine using the clamp enclosed also in this pack.
The colour of the wet strip is then compared with the colour chart and the pH printed below the corresponding colour is read off.
This pH reading and the number of measuring spoonfuls of granules taken should be entered in the control calendar. The patient ought to bring the control calendar every time he visits the doctor.