Posology : מינונים

2     DOSAGE AND ADMINISTRATION
2.1 Treatment of Osteoporosis in Postmenopausal Women
The recommended dosage is: one 70 mg tablet once weekly
2.2 Treatment to Increase Bone Mass in Men with Osteoporosis
The recommended dosage is: one 70 mg tablet once weekly
2.3 Important Administration Instructions
Instruct patients to do the following:
• Take FOSALAN at least one-half hour before the first food, beverage, or medication of the day with plain water only [see Patient Counseling Information (17.2)]. Other beverages (including mineral water), food, and some medications are likely to reduce the absorption of FOSALAN [see Drug Interactions (7.1)]. Waiting less than 30 minutes, or taking FOSALAN with food, beverages (other than plain water) or other medications will lessen the effect of FOSALAN by decreasing its absorption into the body.
• Take FOSALAN upon arising for the day. To facilitate delivery to the stomach and thus reduce the potential for esophageal irritation, a FOSALAN tablet should be swallowed with a full glass of water (not less than 200 ml). Patients should not lie down for at least 30 minutes and until after their first food of the day. FOSALAN should not be taken at bedtime or before arising for the day. Failure to follow these instructions may increase the risk of esophageal adverse experiences [see Warnings and Precautions (5.1) and Patient Counseling Information (17.2)].
2.4 Recommendations for Calcium and Vitamin D Supplementation
Instruct patients to take supplemental calciumif dietary intake is inadequate [see Warnings and Precautions (5.2)]. Patients at increased risk for vitamin D insufficiency (e.g., over the age of 70 years, nursing home-bound, or chronically ill) may need vitamin D supplementation. Patients with gastrointestinal malabsorption syndromes may require higher doses of vitamin D supplementation and measurement of 25- hydroxyvitamin D should be considered.
2.5 Administration Instructions for Missed Doses
If a once-weekly dose of FOSALAN is missed, instruct patients to take one dose on the morning after they remember. They should not take two doses on the same day but should return to taking one dose once a week, as originally scheduled on their chosen day.