Posology : מינונים

4.2     Posology and method of administration

For ocular use only. Not for injection. VIGAMOX 5 mg/ml eye drops, solution should not be injected subconjunctivally or introduced directly into the anterior chamber of the eye.

Dosage and administration: Instill one drop in the affected eye 3 times a day for 4 days.

Pediatric Use: VIGAMOX Solution has been shown to be safe and effective in pediatric patients including neonates. There is no evidence that the ophthalmic administration of VIGAMOX Solution has any effect on weight bearing joints, even though oral administration of some quinolones has been shown to cause arthropathy in immature animals.
No dosage adjustment is necessary.

Geriatric Use: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.

Special Populations:
Patients with renal impairment:
The pharmacokinetic parameters of oral moxifloxacin are not significantly altered by mild, moderate or severe renal impairment. No dosage adjustment of VIGAMOX Solution is necessary in patients with renal impairment.

Patients with hepatic impairment:
Pharmacokinetic parameters of oral moxifloxacin were not significantly altered in patients with mild to moderate hepatic insufficiency (Child Pugh Classes A and B).


Studies were not preformed in patients with severe hepatic impairment (Child Pugh Class C).
Because of the low systemic exposure by the topical route of administration, no dosage adjustment of VIGAMOX Solution is needed in patients with hepatic impairment.


In order to prevent the drops from being absorbed via the nasal mucosa, particularly in new- born infants or children, the nasolacrimal ducts should be held closed for 2 to 3 minutes with the fingers after administering the drops. After cap is removed, if tamper evident snap collar is loose, remove before using the product.

If more than one topical ophthalmic medicinal product is being used, the medicinal products must be administered at least 5 minutes apart. Eye ointments should be administered last.