Posology : מינונים

4.2     Posology and method of administration

Posology
The dosage should be determined by the physician, according to the requirement of the patient.
Pediatric population

No data are available

Method of administration
Cartridges:
Humulin Soluble in cartridges is only suitable for subcutaneous injections from a reusable pen.
If administration by syringe or intravenous injection is necessary, a vial should be used.
Humulin Isophane in cartridges is only suitable for subcutaneous injections from a reusable pen. This formulation should not be administered intravenously.

Humulin Mixtures in cartridges is only suitable for subcutaneous injections from a reusable pen. This formulation should not be administered intravenously.

Vials:
Humulin Soluble should be given by subcutaneous injection but may, although not recommended, also be given by intramuscular injection. It may also be administered intravenously.
Humulin Isophane in vials should be given by subcutaneous injection but may, although not recommended, also be given by intramuscular injection. This formulation should not be administered intravenously.

Subcutaneous administration should be in the upper arms, thighs, buttocks or abdomen. Use of injection sites should be rotated so that the same site is not used more than approximately once a month in order to reduce the risk of lipodystrophy and cutaneous amyloidosis (see section 4.4 and 4.8).

Care should be taken when injecting any Humulin insulin preparations to ensure that a blood vessel has not been entered. After any insulin injection, the injection site should not be massaged. Patients must be educated to use proper injection techniques.

Humulin Isophane may be administered in combination with Humulin Soluble. (See Section 6.6 Instructions for use and handling - for Mixing of Insulins).

Humulin Mixture formulation is a ready-made defined mixture of Humulin Soluble and Humulin Isophane insulin designed to avoid the need for the patient to mix insulin preparations. A patient's treatment regimen should be based on their individual metabolic requirements.

Each pack contains a patient information leaflet with instructions on how to inject insulin.