Posology : מינונים

4.2     Posology and method of administration
Usage is restricted to qualified health care professionals and to hospitals and clinics with specialised obstetric units with facilities for continuous monitoring.

The recommended dose should not be exceeded, and the dosing interval should not be shortened as this increases the risk of uterine hyperstimulation, uterine rupture, uterine haemorrhage, foetal and neonatal death.
For labor induction at or near term, the initial dose of 1 mg of Prostin E2 Vaginal Gel should be administered by gentle expulsion of the entire content of the syringe into the posterior fornix of the vaginal canal. The patient should remain in supine position for at least 30 minutes. After 6 hours, a second dose of either 1 or 2 mg of Prostin E2 Vaginal Gel may be administered if necessary:
- 2 mg in case of absence of response to initial dose;
- 1 mg to augment an already present response to the initial dose.

SYRINGE ASSEMBLY INSTRUCTIONS:

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1.    Remove peel-off seal.
2.    Remove protective end cap (to serve as plunger rod).
3.    Insert protective end cap into the syringe.
4.    Administer syringe content.