Contraindications : התוויות נגד

4.3      Contraindications

Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1.
Prostin E2 Vaginal Gel should not be used where the patient is sensitive to prostaglandins or other constituents of the gel.


Prostin E2 Vaginal Gel is not recommended in the following circumstances: • For patients in whom oxytocic drugs are generally contra-indicated or where prolonged contractions of the uterus are considered inappropriate such as: - Cases with a history of Caesarean section or major uterine surgery.
- Cases where there is cephalopelvic disproportion.
- Cases in which foetal malpresentation is present.
- Cases where there is clinical suspicion or definite evidence of pre-existing foetal distress.
- Cases in which there is a history of difficult labour and/or traumatic delivery.
• In patients with a past history of, or existing, pelvic inflammatory disease, unless adequate prior treatment has been instituted.
• In patients where there is clinical suspicion or definite evidence of placenta praevia or unexplained vaginal bleeding during this pregnancy.
• Patients with active cardiac, pulmonary, renal or hepatic disease.