Contraindications : התוויות נגד

4.3 CONTRAINDICATIONS
MORPHINE INJECTIONS 20 MG/ML is contraindicated in patients with:
Significant respiratory depression [see Warnings and Precautions (4.4)] Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see Warnings and Precautions (4.4)]
Concurrent use of monoamine oxidase inhibitors (MAOIs) or use of MAOIs within the last 14 days [see Warnings and Precautions (4.4); Drug Interactions (4.6)]
Known or suspected gastrointestinal obstruction, including paralytic ileus [see Warnings and Precautions (4.4)]
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1(e.g., anaphylaxis) [see Adverse Reactions (4.5)]

Due to the high concentration of the 20 mg/ml injection, this formulation is contraindicated for use during labor. Due to the high concentration of the 20 mg/ml injection, this formulation is contraindicated for use in all pediatric patients who cannot reliably participate in the correct assessment of their own pain relief.

Neuraxial administration of MORPHINE INJECTIONS 20 MG/ML is also contraindicated in patients with:
• Infection at the injection microinfusion site [see Warnings and Precautions (4.4)] • Concomitant anticoagulant therapy [see Warnings and Precautions (4.4)] • Uncontrolled bleeding diathesis [see Warnings and Precautions (4.4)] • The presence of any other concomitant therapy or medical condition which would render epidural or intrathecal administration of medication especially hazardous.