Posology : מינונים

2      DOSAGE AND ADMINISTRATION
For continuous intravenous infusion.
HES solutions should be used at the lowest effective dose for the shortest period of time.
Treatment should be guided by continuous haemodynamic monitoring so that the infusion is stopped as soon as appropriate haemodynamic goals have been achieved.


The initial 10-20 ml is to be infused slowly, keeping the patient under close observation (due to possible anaphylactoid reactions).
The daily dose and rate of infusion depend on the patient’s blood loss, on the maintenance or restoration of haemodynamics and on the haemodilution (dilution effect).
The maximum daily dose is 33 ml / kg b.w. / day.
The duration of treatment depends on the duration and extent of hypovolaemia, the haemodynamics and on the haemodilution.
There is currently no clinical experience for application lasting several days.


Paediatric dose:
The dosage in children should be adapted to the individual patient colloid needs, taking into account the disease state, as well as the haemodynamic and hydration status (see section 5.1).
In 41 newborns to infants (< 2 years), a mean dose of 16 ± 9 ml/kg was administered. In 31 children from 2 – 12 years of age a mean dose of 36 ± 11 ml/kg was administered. The dose in adolescents > 12 is the same as the adult dose.