Indications : התוויות

4.1   Therapeutic indications

Therapy is indicated only when an organism resistant to all other antibiotics is suspected. Linezan is indicated in adult and pediatric patients for the treatment of infections when known or suspected to be caused by susceptible organisms including those associated with concurrent bacteraemia such as:
1) Pneumonia - community acquired and nosocomial pneumonia including multi drug resistant streptococcus pneumonia (MDRSP).
2) Skin and soft tissue infections including diabetic foot infections.
3) Enterococcal infections.
Combination therapy may be indicated if a concomitant Gram negative pathogen is documented or suspected.
Linezolid is active against Gram–positive bacteria only. Linezolid has no clinical activity against Gram–negative pathogens. Specific Gram-negative therapy is required if a concomitant Gram-negative pathogen is documented or suspected (See section 4.4 and 5.1).

Linezolid should only be initiated after consultation with a relevant specialist such as a microbiologist or infectious diseases specialist.

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Consideration should be given to official guidance on the appropriate use of antibacterial agents.