Special Warning : אזהרת שימוש

4.4   Special warnings and precautions for use
Long-term continuous therapy with topical corticosteroids should be avoided, with a usual maximum duration of 4 weeks irrespective of age. Adrenal suppression can occur, even without occlusion. If used on children up to the age of 4 years or on the face, courses should be limited to 5 days and occlusion should not be used.

Neriderm may be applied under an occlusive dressing. However, each dressing should not be left on for more than 24 hours. Although occlusive dressings may be used repeatedly, it should be noted that systemic corticoid absorption is likely to be increased with a consequent increased risk of adrenal suppression. If occlusive treatment is expected to be prolonged, it is advisable to change the dressing every 12 hours.

Neriderm should not be allowed to come into contact with the eyes.

Topical corticosteroids may be hazardous in psoriasis for a number of reasons including rebound relapses following development of tolerance, risk of generalised pustular psoriasis, and local and systemic toxicity due to impaired barrier function of the skin.
Careful patient supervision is important in psoriasis.

Exacerbation of skin infections may occur. Infections or secondarily infected dermatoses require additional therapy with antibiotics or chemotherapeutic agents. This treatment can often be topical, but for heavy infections systemic antibacterial therapy may be necessary. If fungal infections are present, a topically active antimycotic should be applied.

If aggravation of skin irritation develops with the use of Neriderm, treatment should be withdrawn and appropriate therapy installed.

Allergic contact dermatitis due to topical corticosteroids and excipients can occur. In these cases eczema fails to improve or deteriorates with treatment. Corticosteroid hypersensitivity occurs most frequently among patients with stasis dermatitis and leg ulceration. Such an observation should be corroborated with appropriate diagnostic patch testing. The appropriate corticosteroid concentration and the choice of the vehicle is crucial in detecting corticosteroid hypersensitivity in patch tests.

Patients with an allergy to corticosteroids may cross-react to several corticosteroids to which they have not previously been exposed.

After topical application, allergies to cross-reacting systemically applied corticosteroids may occur.


As known from systemic corticoids, glaucoma may also develop by using local corticoids (e.g. after large dosed or extensive application over a prolonged period, occlusive dressing technique or application to the skin around the eyes).

Effects on Driving

4.7   Effects on ability to drive and use machines
None stated.