Contraindications : התוויות נגד

4.3. Contraindications

The use of Dexamethasone Rompharm is contraindicated in patients with hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Anaphylactoid and hypersensitivity reactions have been reported following dexamethasone injection. These reactions, although they occur rarely in patients with a previous history of allergy to any drug, are most common.

Corticosteroids can mask some signs of infection or even induce the appearance of new infections or aggravate existing ones. Therefore, the use of Dexamethasone Rompharm is contraindicated, unless the patient receives adequate chemotherapy treatment and is subject to strict medical surveillance, in systemic fungal infections, disseminated tuberculosis, latent tuberculosis or with tuberculin reactivity, in patients with infestation or suspected digestive parasitic infestation, herpes, measles and chickenpox.

The administration of live virus vaccines, including smallpox, is contraindicated in people who are receiving immunosuppressive doses of corticosteroids. In the case of inactivated bacterial or viral vaccines, corticosteroids can prevent the immune response expected from vaccination (increase in serum antibodies). However, immunization procedures can be undertaken in patients who are receiving corticosteroids as replacement therapy, for example in Addison's disease.

Likewise, prolonged treatment with dexamethasone is not recommended in congestive heart disease, myasthenia gravis, peptic ulcer or oesophagitis, diabetes and ocular herpes simplex.

Idiopathic thrombocytopenic purpura in adult is contraindicated by the intramuscular route.